A Review on Cetylpyridinium Chloride

Susceptibility in vitro of Helicobacter pylori to cetylpyridinium chloride.

The antimicrobial agent cetylpyridinium chloride (CPC) which is used in therapy of oro-pharyngeal infections and for antiseptic treatment of the oral cavity is active against different bacterial species. Determination of the minimal inhibitory concentration (MIC) using the agar dilution technique revealed that the gastric pathogen Helicobacter pylori in vitro is highly susceptible to CPC as ind...

Electrochemical and calorimetric study of oligonucleotide complexation with cetylpyridinium chloride.

The complexation of oligonucleotides and antisense drugs with a cationic surfactant, cetylpyridinium chloride (CPC), has been studied using electrochemistry at a micrometer sized liquid/liquid interface. This method can be used to investigate the effect of chemical and structural modifications on the complexation behaviour of oligonucleotides. For the interaction between CPC and oligonucleotide...

The germicidal effect of a quaternary ammonium compound (cetylpyridinium chloride) on Mycobacterium tuberculosis.

Mycobacterium tuberculosis has enjoyed the distinction, among the nonspore bearing organisms, of being one of the most resistant to chemical disinfection. Quaternary ammonium compounds, widely used as effective germicides against gram positive organisms, have generally proved to be without effect on the tubercle bacillus (Lawrence and Grover, 1951; Smith et al., 1950). Recently, it has been rep...

Scientific Committee on Consumer Safety SCCS OPINION ON Cetylpyridinium chloride - Submission II

Formulation and characterization of cetylpyridinium chloride bioadhesive tablets.

PURPOSE Bioadhesive polymers play an important role in biomedical and drug delivery applications. The aim of this study is to develop a sustained- release tablet for local application of Cetylpyridinium Chloride (CPC). This delivery system would supply the drug at an effective level for a long period of time, and thereby overcome the problem of the short retention time of CPC and could be used ...